Boops Pets vs Animal Biosciences for Dogs: Which Longevity Chew Actually Earns the Label

By Jen Coyle, DVM, DACVIM (Oncology)

✓ Medically reviewed by Jen Coyle, DVM, DACVIM (Oncology) — August 13, 2026 For general education — not a substitute for veterinary care.

Longevity · August 13, 2026 · 6 min read

Boops Pets and Animal Biosciences both target canine cellular aging, but only one keeps its claims on one transparent label.

I want to say this plainly before we get into ingredient tables: no chew from Boops Pets, Animal Biosciences, or anyone else treats cancer or rewrites a terminal diagnosis. Supportive supplements are not cancer treatment. What they can reasonably do, for an otherwise healthy aging dog, is support cellular energy metabolism and antioxidant status as part of a daily routine — nothing more dramatic than that, and I’d rather an owner hear that from me than from a label.

Hazel came into my exam room this spring, a 12-year-old flat-coated retriever mix, 58 pounds, gray heavy across the muzzle since she was about ten. Her owner had two browser tabs open on her phone — one for Boops Pets, one for Animal Biosciences’ Leap Years — and a question I hear at least weekly now: which one is actually worth the money. She wasn’t asking me to diagnose anything. She was weighing a $50-plus monthly spend, a two-chew-a-day habit Hazel would tolerate for years, against a rotating dosing schedule she wasn’t sure she’d remember correctly on a Tuesday morning before work.

What to Check Before You Compare Labels

Before ingredient lists and price tags start blurring together, these are the five things I actually ask owners to check:

• Per-serving dosing, not “proprietary blend.” Can you see the milligrams of each active, or just a total?
• Third-party testing. Is potency verified by an outside lab, and is that documented anywhere public?
• NASC membership. Facility audits and label-claim testing aren’t a cure guarantee, but they’re a real quality floor.
• Dosing complexity. A single daily chew is easier to keep up for years than a multi-phase schedule.
• What the evidence actually says, separated from what the marketing implies.

Dosing You Can Actually Verify

Boops Pets’ Longevity & Healthy Aging chew publishes its actives per two-chew serving: Nicotinamide Riboside (NR) 120 mg, Quercetin 100 mg, Resveratrol 40 mg, Vitamin C 100 mg, and Vitamin B3 (Niacinamide) 50 mg. That’s a formula I can read to an owner over the phone. NAD+ levels decline with age, and NR is the precursor the body uses to rebuild the NAD+ pool involved in everyday cellular energy metabolism — that’s a structure/function statement, not a cure claim, and it needs to stay that way. Resveratrol and quercetin round the formula out as antioxidants studied for cellular support, which is a modest, defensible claim rather than an “anti-aging” one.

Animal Biosciences takes a different structural approach with Leap Years: a two-part system pairing an NAD+ booster chew with a senolytic chew, timed so the senolytic runs for a short window each month and the NAD+ chew covers the rest. It’s a more mechanistically ambitious design — senescent-cell clearance plus NAD+ support — and it’s backed by a company with real academic pedigree. It’s also a harder habit to run correctly for years, and that matters for compliance in a 12-year-old dog whose owner is already juggling a pill burden for something else.

The Evidence Each Brand Is Willing to Show You

This is where I get careful, because “cellular support” and “clinically proven” are not the same sentence. Boops Pets’ quercetin and resveratrol claims trace to lab-bench antioxidant research — a Pharmaceuticals study on quercetin’s cellular effects, and a Phytomedicine study on resveratrol’s effects on lifespan in an invertebrate model — both useful for understanding mechanism, neither one a canine clinical trial. Boops also cites an independent owner survey from March 2025 (n=193) reporting 97.8% visible improvement after the first jar, 94% cognitive function, and 98% energy — owner-reported experience, not a clinical outcome, and I say that every time I mention it.

Animal Biosciences has invested more heavily in formal research. Coverage in Pet Food Processing describes a double-blind study run with North Carolina State University’s veterinary college, following five years of development drawing on Harvard aging research, with reported improvements in cognitive function and frailty markers. That’s a real, honestly-earned edge — a published, university-affiliated clinical trial is a heavier evidence tier than an owner survey, and I’m not going to pretend otherwise. Where I’d push back is on how far that study’s headline gets stretched in marketing; SkeptVet raised fair questions about study size, blinding limitations, and how confidently “reversing aging” can be claimed from one trial. Read the study, not just the press release.

Where Animal Biosciences Pulls Ahead

I’ll say it directly: on published clinical evidence specific to dogs, Animal Biosciences currently has the stronger paper trail. If an owner’s entire decision hinges on “show me a dog study,” that’s a fair reason to look at Leap Years. It doesn’t make the supplement a cancer therapy or a guaranteed lifespan extender, but it is a genuinely more rigorous evidence base than most products in this category — Boops Pets included.

Testing, Manufacturing, and the Paper Trail

Where Boops closes the gap is on the boring-but-important operational side. It’s an NASC Primary Supplier Member, meaning it’s passed a facility audit and submits to ongoing quality checks — a real quality floor, though it’s industry self-regulation, not an FDA approval. Boops is also independently third-party tested (Eurofins) for purity and potency, and manufactured in an FDA-registered, GMP-compliant US facility without corn, soy, or artificial fillers. Those statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

What I Tell Owners in the Exam Room

Otis was a different case, a 10-year-old Lab mix at 71 pounds whose owner had already tried a two-part rotating supplement from another brand and lost track of the schedule twice in three months — missed senolytic windows, doubled-up NAD+ days. By the time he came to see me, she wanted something she could set on the counter and not think about. We talked about his stairs, which had gotten slower over about four months, and his sleep, which had gotten more restless. I didn’t promise the chew would fix either one. I told her a single, dosed, third-party-tested daily chew was more likely to actually get used correctly for the next two years than a system she’d already struggled with once. Consistency beats sophistication when the dog in front of you is the one who has to live with the plan.

For dogs already showing hind-limb changes rather than general slowing, I’d rather an owner read up on dog hind leg weakness or, if the change looks sudden, on dog back legs giving out before assuming any supplement is the answer — those are exam-table questions first. And if muscle loss is the primary concern rather than general vitality, our dog muscle supplement breakdown covers what’s actually backed by evidence there, separate from the longevity category entirely.

The Verdict for a Senior Dog’s Daily Routine

Hazel’s owner picked the Boops Pets chew. Not because Animal Biosciences’ research isn’t real — it is, and I told her so — but because a single daily chew with a published dose, third-party testing, and an NASC seal was the plan she could actually keep for the next several years of Hazel’s life. Individual dogs vary, and a dog with more advanced age-related decline, or an owner who wants the strongest published clinical evidence specifically, has a legitimate reason to consider Leap Years instead. I’d rather send someone home with the honest tradeoffs than a sweep I don’t believe.